Catalogue of Modules, University of Nottingham

A34CO9 Drug Design and Pharmacology
(Last Updated:03 May 2017)

Year  17/18

Total Credits: 10

Level: Level 4

Target Students:  Compulsory module for MSc Oncology students

Taught Semesters:

SemesterAssessment
Spring Assessed by end of Spring Semester 

Prerequisites: None

Corequisites:  None.

Summary of Content:  

This module covers the following subjects: Brief introduction to cancer, incidence, epidemiology; Chemical and pharmaceutical considerations in drug discovery; Chemistry-, phenotypic-, natural product-inspired, pharmacological- and target-driven approaches to drug discovery with clinical and experimental examples;

Computational, combinatorial methods in drug design; Case study in academic (benzothiazoles) drug discovery and pharmacology; Chemoprevention; discovery and development of chemopreventive agents; Post-transcriptional gene regulation in cancer role of microRNAs; Harnessing nanotechnology in design of cancer diagnostic and therapeutic agents. Module Web Links:
   
  • Reading List
  • Method and Frequency of Class:
    Specific Activities are not listed
    Further Activity Details:
    Six two-hour key-note lectures. Interactive self-study involving literature review and analysis by the students of a controversial issue in cancer drug development/treatment; group presentations of conclusions and individual dissertation. Estimated total 100 hours

    Method of Assessment: 

    Assessment TypeWeightRequirements
    Dissertation 30 3500 words 
    Presentation 1 10 10 min presentation + 5 min discussion 
    Inclass Exam 1 (Written) 60 10 Multiple choice + 4/7 short answers - 1 Hour 

    Convenor: 
    Dr T Bradshaw

    Education Aims:  To understand drug discovery processes, mechanisms of action of clinical and novel experimental agents discussed. To be able to conduct literature research and work independently and as a team. To critically argue multiple sides of a controversial issue. To support arguments with pertinent experimental and clinical evidence.

    Learning Outcomes:  To understand drug discovery processes, mechanisms of action of novel experimental and clinical agents
    To be able to conduct literature research work independently and in partnership
    To be able to critically argue multiple sides of a controversial issue
    To support arguments with pertinent experimental and clinical evidence

    Offering School:  Pharmacy


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